Hemolytic Anaemia Profile

Hemolytic Anaemia occurs when red blood cells die at a faster rate than they are produced in the body.

Below tests are conducted for its diagnosis:

Complete blood count – The CBC gives information about the number of red blood cells, white blood cells, and platelets along with the hematocrit and the indices in your blood.The correlation of all these parameters give clues to the diagnosis of hemolytic anaemia.

Reticulocyte count – A reticulocyte count measures the number of young red blood cells in your blood. The test shows whether your bone marrow is making red blood cells at the correct rate.

Total biliruin levels – It measures the level bilirubin(Direct & Indirect) in the blood.

Unconjugated bilirubin – It is a criterion for the diagnosis of hemolytic anaemia, but it is not specific because an elevated indirect bilirubin level is also elevated in other conditions.

G6PD Quantitative assay – A deficiency in G6PD causes RBCs to become more vulnerable to breaking apart (hemolysis) under certain conditions. Thus it needs to be tested.

Abnormal hemoglobin levels – To investigate hemoglobinopathy (have an abnormal form of hemoglobin).

LDH levels – Serum LDH elevation is a criterion for hemolysis.

Serum Haptaglobulin – A low level of haptoglobin in the bloodstream is a sign of hemolytic anaemia.

Coombs test – To help diagnose the cause of hemolytic anaemia as caused by autoimmune disease or induced by drugs; to investigate a blood transfusion reaction; to diagnose hemolytic disease of the newborn.