Pro-calcitonin is a protein. The test detecting it is used to identify the risk of development of systemic bacterial infection. It is primarily carried out in emergency departments, intensive care units and in cases which show symptoms that may be due to sepsis.

Conditions in which it is indicated

  • Localized mild-to-moderate bacterial infection
  • Noninfectious systemic inflammatory response
  • Untreated end-stage renal failure
  • Bacterial sepsis
  • Severe localized bacterial infection (eg, severe pneumonia, meningitis, peritonitis)
  • Severe noninfectious inflammatory stimuli (eg, major burns, severe trauma, acute multiorgan failure, major abdominal or cardiothoracic surgery)
  • Medullary thyroid carcinoma